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For measuring intracellular GSH content of different kinds of cells, cells were collected after 24 h with rinsed twice by PBS and the cell numbers were calculated using a cell counter
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In view of the pivotal role played by GSH in redox system and the relationship between oxidative stress and autophagy 68 , it is conceivable that GSH depletion-induced oxidative stress and lipid peroxidation may be a key point linking ferroptosis and autophagy in RPE cells
Preclinical studies with BPC-157, which shares the identical active sequence, have demonstrated protective effects against various forms of neural damage
