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Treatments in these co-cultures included PBS as a control, FOXO4-DRI at 50 M, hydrogen peroxide (H2O2) at 50 M to induce senescence, and a combination of H2O2 with FOXO4-DRI
Many skincare professionals actually recommend using them together for stubborn pigmentation problems
Over 24 hours at room temperature, NAD + showed tendency to increase by approximately 25% and NADH by 125% from the baseline at collection, while NADP + remained stable and NADPH levels decreased 69% (Supplementary Figure 1a-f)
Focus: Managing expectations, emphasizing non-scale victories, continuing protocol despite slower visible progress
However, it is not the target maintenance dose
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