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Maintained glutathione levels in both cytosol and mitochondria, preventing redox imbalance caused by TRX2 deficiency
Long-term cardiovascular outcome data is limited
It is critical for cellular functions (Hargreaves et al., 2020), particularly in energy production through adenosine triphosphate synthesis (Zhang et al., 2013)
Perimenopause is the transition years leading up to menopause
Three major functional domains represent the essence of the KEAP1 protein structure: the N-terminal Broad complex/Tramtrack/Bric brac (BTB) domain, the central intervening region (IVR) and the C-terminal Kelch/Double glycine repeat (DGR) domain [121, 122]
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