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Whilst vitamin B12 toxicity is exceptionally rare, very high levels from supplements or injections have been associated with skin reactions such as acne-like eruptions

We have previously demonstrated an increased nicotinamide:nicotinic acid ratio in the adipose tissues of 5A-1MQ-treated DIO mice 13

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These compounds are of interest to researchers because aging is now understood in the literature as a set of measurable cellular processes, not a single mechanism, making peptide research in this space inherently multi-pathway