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Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide receptor agonists protect synaptic plasticity in animal models of Alzheimers disease The previous section showed that GLP-1 and GIP signaling has direct effects on synaptic transmission and LTP in the hippocampus

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To fill this knowledge gap, Chii-Min Hwu, National Yang-Ming Chiao Tung University, Taipei, Taiwan, and colleagues sought to investigate the long-term outcomes of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes and cirrhosis

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