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Clinical Impact of ITCA 650, a novel drug-device GLP-1 receptor agonist, in uncontrolled type 2 diabetes and very high baseline HbA1c: The FREEDOM-1 HBL (high baseline) study
It mimics the action of the natural hormone GLP-1, enhancing insulin secretion when blood sugar levels are high, reducing glucagon release, and slowing gastric emptying
These effects include energy metabolism, mitochondrial homeostasis, epigenetic regulation, endocrine regulation, inflammation and immune homeostasis, signal transduction, and neuromodulation (Fig
Bernstein AM, Sun Q, Hu FB, et al
Understanding this timeline helps explain why these medications have suddenly become household names and whether they might fit into your health journey
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