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What we DO know, however, is that only 20% (or even less) of the people with symptomatic B12 deficiency have anaemia or altered size of the red blood cells
The STEP trials for Wegovy, which included thousands of participants, showed average weight loss of approximately 15 to 17 percent of body weight over 68 weeks and produced detailed safety data regarding side effects, contraindications, and long term outcomes
In addition to aligning with regulatory conclusions, the new study by Kerem and co-author Joshua Stokar, MD (Hadassah University Medical Center), adds to other analyses suggesting favorable mental health effects of GLP-1 receptor agonists, including one that showed a lower risk of incident and recurrent suicidal ideation in adults who were overweight or obese and taking semaglutide and another that showed no causal link between semaglutide or liraglutide and reporting of suicidal ideation and depression
Potential Side Effects and Safety Considerations The most common side effects are gastrointestinal nausea, vomiting, and diarrhoea with additional monitoring warranted for pancreatitis, gallbladder disease, heart rate changes, and diabetic retinopathy
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