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No systemic side effects were consistently reported across any of the studies
Weight loss : Improves fat metabolism, supports glucose regulation, and may inhibit myostatin, a protein that limits muscle growth
It strengthens the intestinal mucosal barrier, preventing the translocation of lipopolysaccharides (LPS) into systemic circulation (metabolic endotoxemia), a key driver of insulin resistance (440)
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However, the reproductive toxicity of Tripterygium wilfordii limits its clinical application, and its mechanism of reproductive toxicity is not fully understood [118]
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