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He now needs a cane to help him walk

These disruptions lead to water and sodium influx, potassium efflux, cell swelling, membrane potential changes, and eventual cell lysis, which then releases intracellular contents, eliciting an inflammatory phenotype through DAMP release and triggering immune responses (Murao et al., 2021)

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*OASIS 4 clinical trial (2025)

Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimer s diseaseprotocol for a controlled, randomized double-blinded trial