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It has an hepatic metabolism, mainly because of the glucuro-conjugation of the molecule, with the formation of inactive metabolites
While supplementing with up to 2,000 mcg of B12 is considered safe for treating deficiencies, it is advisable to consult a healthcare professional to determine if supplementation is necessary, especially if you are taking medications or are pregnant
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Resolution or significant improvement in nagging injuries or chronic pain
The theory is that this keeps your body sensitive to the peptide and helps you lock in your progress, though this hasn't been proven
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