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Researchers used an indirect comparison to evaluate their relative efficacy in patients with T2D inadequately controlled on metformin monotherapy, with change in HbA1c and body weight at approximately one year as the primary outcomes
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But the full picture is more nuanced than that
doi: 10.1016/j.clnu.2021.05.015 68 KlementRJMeyerDKanzlerSSweeneyRA
It stimulates lipolysis (breakdown of stored fats) and inhibits lipogenesis (formation of new fat), primarily via activation of -adrenergic and AMP-activated protein kinase (AMPK) pathways
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