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The PNPLA3 gene encodes for the membrane bound PNPLA3 enzyme, which is mainly expressed in the liver (where it is involved in hepatic steatosis) and adipose tissue (where it mediates acylglycerol hydrolysis)
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Additional preclinical themes include angiogenesis (through endothelial cell migration and tube formation), modulation of inflammatory signalling, and reported effects on cardiac, dermal and neural tissue in animal models
EV4F,G)
Avoid mixing it directly with strong actives like vitamin C or retinoids in the same routine, as this may reduce effectiveness or cause irritation
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