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This generally is not critical in testing male Caucasians, but it certainly is a problem in diagnosing some Caucasian females and blacks of both sexes, especially during the reticulocytosis following acute hemolysis

Around week five my wife pointed out that the skin on my arms felt different when she grabbed them

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This is most evident for GABA, with both intra-session CoV higher than both inter-session CoV, but when scaled to water, the absolute difference is small (i.e., highest mean intra-session CoV of 11.5% compared to highest mean inter-session CoV of 11.0%)