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To be more exact: Similar to the Phase 2 trial for obesity, the weight loss did not plateau and could have been far greater in the Retatrutide groups if the trial was allowed to continue Given that Type 2 diabetics are known to lose less weight than obese people without diabetes, the bodyweight changes seen in this study are to be expected

N Engl J Med 387(12):10891098 Rodriguez PJ, Goodwin Cartwright BM, Gratzl S, Brar R, Baker C, Gluckman TJ et al (2024) Semaglutide vs tirzepatide for weight loss in adults with overweight or obesity

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