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Keep in mind that self-tanners may or may not provide protection from the sun

One legitimate concern the authors raise is discontinuation

MC1R-Linked Melanogenesis Model: Researchers commonly use MT2 as a reference compound in melanocyte studies examining melanin production and UV-related signaling

Quarterly check-ins after the first year After 12 months, if your weight has remained stable, you can likely shift to quarterly monitoring

Sun Y, Mu Y, Ma S, Gong P, Yan G, Liu J et al (2005) The molecular mechanism of protecting cells against oxidative stress by 2-selenium-bridged -cyclodextrin with glutathione peroxidase activity