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From June to July, prescribing increased sharply (+0.11 percentage points), representing the largest single-month increase observed during the study period

Menzel H et al

GLP-1 medicines belong to a group of metabolic hormone therapies that mimic hormones your body already produces after eating

Volunteers were randomized to either receive a placebo or one of three varying doses of orforglipron, taken once a day (as is common with GLP-1 therapy, people gradually reached their maximum dose over time)

After a period on semaglutide, you can then switch back to tirzepatide and potentially experience renewed dual agonist benefits from recovered GIP receptors