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Nonetheless, the underlying reasons for the inconsistencies in the reported associations between T2DM and levels of plasma DPP-4 activity (lower, unaltered, higher) have not been adequately explained, although one study did suggest that it might be related to the populations studied, with changes only becoming evident once moderate or severe hyperglycaemia becomes established (68)
On average, prescription medications, especially GLP-1 and dualaction drugs like tirzepatide, produce greater weight loss than lifestyle programs alone
Cost discussions should still start with approval status and medical fit
Fastings role in health: where it shows promise and where it likely offers no distinct advantage over caloric restriction [1:23:45]
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