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Selecting agents predominantly based on safety and ease of monitoring makes sense
Curr Opin Physiol 12:3943
This is what pharmacologists call an orphan receptor a receptor with no identified endogenous ligand
Current areas of scientific investigation include cytoskeletal signaling pathway analysis, extracellular matrix interaction studies, peptide signaling coordination research, cellular mobility and organization investigations, multi-pathway signaling research, and peptide interaction and pathway convergence studies
Chronic tinnitus persists for months, or longer and involves more complex changes in the brain and nervous system
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