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Shridharani in Manhattan, is an enzyme that breaks down collagen (specifically Type 1 and Type 3) in specific tissues to help the body create new and better-quality skin

This can be due to: Gastrointestinal conditions such as Crohns disease or celiac disease

However, this deficiency may be more likely to affect females at certain times, Potential symptoms of B12 deficiency in females fatigue or weakness confusion or issues with memory mouth or tongue soreness headaches diarrhea shortness of breath vision problems numbness or tingling depression or anxiety balance and coordination problems Other signs of B12 deficiency B12 deficiency can cause anemia, a condition where the body cannot create enough healthy red blood cells

So why on earth is the BOP trying to restrict B12 as methylcobalamin

Those are: under eyes and lips for patients who need superficial injection and/or who have very thin skin