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[ref] CYP2E1 and oxidative pathway: The liver breaks down most of the acetaminophen using sulfation and glucuronidation reactions, allowing for easy excretion
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the aggregating alpha-synuclein also binds preferentially to mitochondria where it can disrupt energy metabolism leading to oxidative stress
Mitochondria are your cells power plants - tiny organelles that convert food and oxygen into ATP, your bodys energy currency
The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
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