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According to earlier data, therapeutics targeting the Nrf2/AOX1 pathway can reduce asthma by increasing airway epithelial barrier integrity (Mizumura et al

Total glutathione values (BSO did not cause oxidation of glutathione, data not shown)

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In addition to its detoxification abilities, it also scavenges and neutralizes free radicals and helps with the recycling of other antioxidants (vitamins C and E) to keep them in their active form

The time courses of weight reduction with ZEPBOUND and placebo from baseline through Week 72 are depicted in Figure 3 for Study 1 and Figure 4 for Study 2