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We found that AA-exposed mice exhibited significantly greater airway hyperreactivity compared to PBS and melatonin-only controls ( Figure 1O ), alongside reduced dynamic compliance ( Figure 1P )

While clinical data remain limited, DSIP shows promise in supporting recovery, hormonal balance, and overall well-being

Patients with known PPARG loss-of-function variants (associated with partial lipodystrophy) should be monitored for atypical fat redistribution during treatment, as lipolytic stimulation in the context of impaired adipogenesis carries theoretical hepatic lipid accumulation risk

High consumer interest in weight management and metabolic health

In preclinical models its reported effects concentrate at or near the site of administration, where it appears to promote new vessel formation, support fibroblast activity and stabilise the local healing environment