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The results showed no significant dependence of the cellular uptake of nanoparticles on the oxygen concentration in the cells (Supplementary Fig

Dosing matters because GHK-CU works through cellular signaling rather than direct mechanical action

CG-C: Methodology, Writing original draft

Notably, NRF2-inducing compounds, such as tBHQ and sulforaphane, modify distinct KEAP1 residues from oxidation by ROS, thus allowing for an additive effect in the presence of oxidative stress (Suzuki et al., 2019