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Cortisol promotes visceral fat storage , raises insulin resistance, encourages quick-energy eating, and increases appetite for high-calorie foods

The smaller final step from 8mg to 12mg (a 50% increase rather than a 100% doubling) reflects the finding that GI tolerability improves at higher doses once the body has already adapted to substantial receptor activation

These medications now account for more than 15 percent of annual claims for more than a quarter of employers