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It is essential for DNA synthesis and contributes to overall energy metabolism

Megaloblastic anemia Diminished activity of methionine synthase in vitamin B 12 deficiency inhibits the regeneration of tetrahydrofolate (THF) and traps folate in a form that is not usable by the body ( Figure 3 ), resulting in symptoms of folate deficiency even in the presence of adequate folate

This interesting review is aimed at primary care clinicians but represents a good reference paper for all healthcare professionals utilising B12 supplements and nutritional guidance to resolve B12 deficiency or dietary inadequacy

At CoLaz we give B12 injections only after a free consultation and only where treatment is appropriate

Preparing your multi-dose Wegovy pen You should always use a fresh needle with every dose to prevent contamination or infection