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Supporting these intricate cellular processes is vital for overall well-being

Oncogene 22 , 73697375 (2003)

pylori colonization also negatively affects the expression of antioxidant proteins, along with epigenetic modifications and DNA methylation, such as GATA-4, GATA-5 and TWIST-1 (88), as well as miRNAs dysregulation, such as mir-21, mir-92a, mir-27a, mir-146a, mir-326, mir-155 and mir-663 (73, 89)

Subsequently, reactive oxygen species (ROS)-related innate immune signaling, including the expression of TLR4, and the activation of NF-B, ERK1/2, p38 MAPK, and JNK in the liver, were all inhibited by H 2 treatment

This activation has been shown to upregulate genes involved in collagen synthesis, cell proliferation, and differentiation while potentially downregulating matrix metalloproteinases