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The Drugs.com JMIR sample captured a more frustrated version: "It has done absolutely NOTHING for me for weight loss." This is the camp the STEP 1 trial captures too, roughly 13.6 percent of participants on semaglutide failed to hit the 5 percent weight loss threshold by week 68

In addition, GLP-1 RAs have shown to present direct anti-inflammatory effects, by modulating immune cell signalling and preventing the release of reactive oxygen species (ROS) (10)

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