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At 1 g/ml, hTERT expression was upregulated 12-fold in 21NT and at 0.5 g/ml, BT474 showed a fivefold upregulation relative to the untreated cells (Fig

In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]

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