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Moreover, it is recognized to be a pantothenate kinase inhibitor, a long-chain-fatty-acid--CoA ligase inhibitor, a ferroptosis inhibitor, a cardioprotective agent, an antidepressant, and a geroprotector (National Center for Biotechnology Information, 2023g)
Much of the clinical rationale rests on shorter-term pharmacology, mechanism-based reasoning, and accumulated compounding-pharmacy clinical experience rather than gold-standard RCT data
Much of the reported 40% lean mass loss with GLP-1 use is coming from the liver, explained exercise physiologist Keith Baar, a professor of Neurobiology, Physiology and Behavior and Physiology and Membrane Biology
But case reports cannot establish causation, so definitely causes overstates the evidence just as totally safe ignores it
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