Researchers should note that despite GHK-Cus favorable safety profile, the subcutaneous or intramuscular administration of peptides in general is associated with injection site pain, lightheadedness, nausea, and even flu-like symptoms in subjects
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Interaction tests for these variants were performed on an unrelated subset of HUNT participants ( N = 26,235) in PLINK v1.9 with sex, age, batch, and 4 principle components as covariates and a sex interaction term
According to Gruchlik et al, GHK-Cu decreases TNF-alpha-dependent IL-6 secretion in fibroblasts, and is preferable for use on the skin to corticosteroids or non-steroidal anti-inflammatory drugs, which have greater side effects [9]