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Thus, in our in vitro model of DR, ARPE-19 cells were cultured in DMEM/F12 nutrient mixture having the recommended standard glucose concentration of 17.5 mM, as control condition
GHK-Cu stands for glycyl-L-histidyl-L-lysine bound to copper (II) a naturally occurring tripeptide complex first identified in human plasma in the 1970s
C ch hot ng ca cht Glutathione 1
Collectively, these results suggested that APR-017 and LCS3 treatment induce vulnerability of VRK2-deficient PC cells by GSH inhibition and consequent disruption of the balance between ROS generation and antioxidation
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