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WARNING Research Use Only (RUO): This product is a laboratory research material

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As E2 and E3 mice are known to have increased longevity relative to E4 mice (Shinohara et al., 2020), this overall increase in cerebrovascular acylcarnitines could represent compensatory changes to supplement energetics with age, or act as a FA detoxification mechanism, a response which appears blunted in E4s

In a 12-week murine study, systemic IGF-1 elevation produced a 22% increase in dermal collagen density measured by hydroxyproline assay