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due to NDMA (cancer causing carcinogen) impurities
They are much gentler on the digestive system and better tolerated, making them the best choice for those with digestive symptoms or sensitive guts
In all models, the following fixed covariates were entered: assigned treatment (investigational product or placebo), baseline measurement of the outcome of interest, visit (day 14 1 day or day 28 1 day), visit in interaction with treatment, period (period 1 or period 2), sex and, for MIDT outcomes, incentive level
Every batch is verified to ensure consistent, reliable dosing and the highest level of safety
These same types of modifications (fatty acid chains, albumin binding) that work for pure GLP-1 agonists also extend tirzepatides duration
