It is not magic, not weight loss, and not for everyone
Progesterone is often sedating, which is helpful for insomnia, but may not be tolerated by everyone
Maintenance looks different for everyone, Thissen says, and might include switching to a different type of weight loss medication, like metformin, or a dietary supplement, like berberine
(A 2022 clinical trial published in the New England Journal of Medicine found that roughly 80% of people taking Zepbound did.) Research and obesity medicine specialists have identified a few common patterns for when symptoms tend to flare up: Early on, especially during the first few weeks Within 48 hours of an injection After a dose increase Individual bouts of nausea, diarrhea and vomiting often pass within a few days, though constipation can stick around much longer