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GLP-1 medications may cause rapid weight loss, which can result in a hollowed look to the face, sunken eyes, wrinkles, sagging skin and changes in the size of your lips, cheeks and chin

The FDA labels for semaglutide products note that mean increases in resting heart rate of 1-4 beats per minute have been observed, with some patients experiencing larger increases

Metformin and weight loss in obese women with polycystic ovary syndrome: comparison of doses