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Further research, including prospective studies and registry data, is needed to better understand the safety profile, potential benefits, and risks of GLP-1 therapy in individuals with Crohn's disease

Patient perspective Following the patients weight gain induced by adjuvant therapy, she reported significant limb swelling that required daily use of compression garments and resulted in a substantial quality of life impairment

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- WebMD, accessed April 22, 2025, Life After Wegovy and Zepbound - WebMD, accessed April 22, 2025, GLP-1 Diet: Foods to Eat and Avoid on Weight Loss Medication, accessed April 22, 2025, Avoid These Foods While Taking Ozempic, accessed April 22, 2025, Weight loss: New dietary guidelines for people taking Wegovy, Ozempic - Medical News Today, accessed April 22, 2025, What is Zepbound

This may lead to ulceration, or, if healing occurs, poor collagen strength in the healed wound, increasing the probability of re-ulceration (Fitridge et al., 2024)