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Lactylation in other diseases Lactylation of histones and non-histone proteins is also linked to other various diseases, including liver diseases such as fibrosis, liver ischemia/reperfusion injury (LI/R) injury, and acetaminophen (APAP)-induced liver injury (AILI), lung fibrosis, acute and chronic kidney injuries, skin injuries such as flap necrosis and hyperplastic scarring, skeletal issues such as osteoarthritis and intervertebral disc degeneration (IDD), and sHLH (Figs

Both drugs affect weight by impacting the glucagon-like peptide-1 system

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It puts language to an experience thousands are having but struggling to explain, and it gives you something even more important, a path forward

Nature 445 (7130), 834842