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The trial data shows a range, not a guarantee

Patients Starting GLP-1 Therapy Some doctors prescribe oral semaglutide as a test run for patients who: Want to assess GLP-1 tolerability before committing to injections Have concerns about nausea and want to try a lower-exposure option first Plan to transition to injections after demonstrating good tolerance This strategy can build confidence, though starting directly with injectable therapy (at the lowest dose) often works just as well

Patients should be counselled to seek immediate medical attention if they experience severe, persistent abdominal pain radiating to the back