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In AD, oral DFP at 15 mg/kg twice daily reduced hippocampal iron (P = 0.03) but paradoxically accelerated cognitive decline, likely due to disruptions in critical iron-dependent processes ( In addition to therapies targeting iron, various lipid peroxidation inhibitors have undergone clinical trials
This makes it useful for recovery from: Traumatic brain injury (TBI) Depression Anxiety Cognitive decline 5
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In the 68-week trials 7,9 , reductions in weight, waist circumference, blood pressure and HbA 1c appeared to plateau around week 60 with semaglutide
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