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Allergic Reactions Individuals allergic to glutathione may have a reaction and develop rashes or itchy skin when they use glutathione supplements

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J Plast Reconstr Aesthet Surg 63:11861195

This powerful effect was particularly important during the peak outbreak of COVID-19 where it was suggested as a possible supplement to help suppress the widespread inflammation often leading to organ failure

This may be due to the complexation of copper to the small biologically active peptide, GHK 45