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Managing GI discomfort during dose escalation supports medication adherence, which is the critical intermediate outcome
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doi:10.1056/NEJMoa2032183. Semaglutide Treatment Effect in People With Obesity (STEP 1)
Six months before his presentation, he began weekly semaglutide injections at a dose of 1.0 mg subcutaneously weekly for weight loss and bioidentical hormone-replacement pellets to correct a testosterone imbalance. He stopped the hormonal replacement therapy after 2 weeks and did not take any other over-the-counter medications or herbal supplements
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