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Manufacturers may invest more heavily in next-generation obesity and diabetes therapies that offer improved convenience, stronger efficacy, or fewer gastrointestinal side effects

Hypersensitivity Reactions: Severe allergic reactions, including anaphylaxis and angioedema, have occurred

10 , CD013650 (2021)

Measurement of L-carnitine and acylcarnitine in body fluids and tissues in children and in adults

This landmark study of over 17,000 adults with established cardiovascular disease and overweight or obesity without diabetes demonstrated a 20% reduction in major adverse cardiovascular events with semaglutide 2.4 mg compared to placebo