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doi: 10.1056/NEJMsb1609216 18
The REWIND trial, targeting cardiovascular events in T2DM participants without previous cardiovascular history, found that dulaglutide reduced cardiovascular outcomes, and was well tolerated [61]
GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed diabetes and weight management, but emerging evidence links these medications to increased gallbladder complications
Vagal afferents, enteric neurons, myenteric plexus nerve fibrils, enteroendocrine cells, and subepithelial myofibroblasts express Glp2r mRNA 33,34
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