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Evidence remains mixed and often limited to small trials or animal models

In a study using a mouse model of systemic lupus erythematosus, endothelial dysfunction was confirmed

This would almost certainly confound the results and make the data very difficult to interpret reliably

Thus, we find that these two molecules have advanced in different areas: Melanotan-1 (SCENESSE, Clinuvel Pharmaceuticals Ltd) is being studied in phase 2 and phase 3 clinical trials as a photoprotective drug for protection against nonmelanoma skin cancer and in other photoinduced skin diseases, such as erythropoietic protoporphyria, solar dermatitis, and polymorphic light eruption

It needs to be refrigerated and can be used for 90 days after opening the bottle