Could be a lower-purity analog or misidentified compound
They can help generate hypotheses and guide more rigorous, controlled research that allows us to draw more definitive conclusions.
Current estimates suggest: Approximately 900,000 people living with dementia in the UK (Alzheimer's Society) Two-thirds of these have Alzheimer's disease (approximately 600,000 people) Projected to rise to 1.6 million by 2040 as the population ages Healthcare and social care costs exceed 26 billion annually Informal caregiving burden is enormous, affecting family members' employment and wellbeing This disease burden explains why the NHS and research community continue pursuing disease-modifying treatments, despite repeated setbacks like the LIFT-AD trial failure

do not discontinue without consulting your provider Monitor blood glucose regularly and report persistent hyperglycemia Test for ketones if nausea, vomiting, or abdominal pain occur Stay hydrated to reduce risk of dehydration and kidney injury Follow up with HbA1C tests every 36 months Drug interactions Diuretics: increased risk of dehydration and hypotension Insulin or sulfonylureas: increased hypoglycemia risk ACE inhibitors and NSAIDs: potential for worsened renal function Sources Farxiga (dapagliflozin) tablets, for oral use [package insert]
Firstly, by restoring the incretin effect whereby oral nutrients elicit insulin release and glucagon suppression [3]