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Diana Girnita, MD, PhD, FACR double board-certified rheumatologist, founder of Rheumatologist OnCall (telehealth practice serving women across multiple US states, in person in California), PhD in immunology
A 2017 meta-analysis found no significant increase in pancreatitis or pancreatic cancer risks (odds ratios 0.93 and 0.94, respectively)
30 EMPIRE randomized 116 ST-segment elevation myocardial infarction patients to exenatide or placebo in parallel groups and showed that at 6 months (n=58), exenatide reduced E/e with improved strain parameters, measured by conventional and speckle tracking echocardiography (NCT01580514)
This figure probably underrepresents the issue because binge eating disorder is the most common of all eating disorders, but it can often go unrecognised, including by patients themselves, Ms Gooding says
The risk is dose-dependent and increases with prolonged use, advanced age, concurrent corticosteroid or anticoagulant use, and history of peptic ulcer disease
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