A Systematic Review of Protein Intake and Muscle Mass in Resistance Training
GLP-1 Preclinical Study Design and Methods To evaluate systemic toxicity and toxicokinetic characteristics of the GLP-1 RA test article and potential reversibility of any findings, we designed an IND-enabling study that included: a robust dosing schedule of daily oral administration for 28 days
Mansour A, Mousa M, Abdelmannan D et al (2023) Microvascular and macrovascular complications of type 2 diabetes mellitus: exome wide association analyses
This expansion is especially important because emerging observational evidence has already shown that GLP-1 receptor agonist exposure may be associated not only with altered symptom trajectories, but also with differences in major joint injections and conversion to arthroplasty in patients with preexisting OA, underscoring the need for future trials to capture pathway-level outcomes rather than pain alone (Porto et al., 2025)
V., Samaddar, M., Sinha, D., Purushotham, J