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Mechanism: NAD is a critical coenzyme in mitochondrial energy metabolism, playing a central role in ATP production and cellular repair processes

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Therefore, the discovery of this parallel GSH-independent mechanism for lipid peroxide scavenging is of great interest for development of ferroptosis-based potential chemotherapeutics

Zhang Y, Gao D, Gao Y, Li J, Li C, Pan Y et al (2024) Gestational diabetes mellitus is associated with greater incidence of dementia during long-term post-partum follow-up