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The diagnosis usually involves the following: clinical findings, the finding of 5-oxoprolinuria, low levels of glutathione, low activity of glutathione synthetase, and mutation analysis of the glutathione synthetase gene
GLP-1s are powerful tools, but long-term success requires preserving lean mass, managing side effects, and having a structured transition plan once dosing tapers
Andrologia 1994;26(3):155-159
PLoS ONE, 9(2), e90900.
Multiple randomised controlled trials and observational studies have examined their hepatic effects, with generally encouraging results
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