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The dual primary endpoints were change in KCCQ-CSS (a standard measure of heart failure-related symptoms and physical limitations) and percentage change in body weight from baseline to 52 weeks

You can help to control and avoid these side effects

1 The World Health Organization has estimated that in 2021, higher-than-optimal body mass index (BMI) caused an estimated 3.7 million deaths from noncommunicable diseases such as cardiovascular diseases, diabetes, cancers, neurological disorders, chronic respiratory diseases, and digestive disorders

In practice, these effects tend to balance out rather than cause problems

Rekha Kumar, M.D